As the 2025 MLB season progresses into Week 12, savvy fantasy baseball managers are on the lookout for potential waiver-wire pickups to bolster their teams. This week, several hitters are highlighted based on their low roster percentages across major platforms like ESPN and Yahoo.

Among the top recommendations is Ryan O'Hearn (BAL), who holds eligibility at both first base and the outfield and is especially valuable this week with only one left-handed pitcher facing him in a favorable schedule. Nathaniel Lowe (WSH) is also a noteworthy pickup, having shown consistent performance despite a lower roster rate. Meanwhile, Miguel Vargas (CHW) continues to perplex fantasy managers by remaining under the 50% threshold, despite his evident potential backed by impressive APR metrics.

For deeper leagues, consider Otto Lopez (MIA) and Thairo Estrada (COL), both having favorable matchups that could yield substantial points. Lopez has been showing signs of form with three consecutive top-100 finishes, while Estrada's return from injury has him primed for production. The landscape on the waiver wire is dynamic, with players like Eric Wagaman (MIA), proving to be solid options for those in need of versatile hitters.

Aaron Civale's recent trade to the Chicago White Sox has set the stage for a fresh chapter in his career. Having played against the team during his tenure in Cleveland, Civale expressed excitement about joining the White Sox and contributing to their efforts. The team has had a rocky start recently, suffering a heart-wrenching 5-4 loss to the Texas Rangers, despite an early lead. Civale is expected to take the mound on Sunday, looking to help the Sox break their losing streak.

The game against the Rangers highlighted some key performances, including Adolis García's walk-off single in the 11th inning and strong contributions from players like Luis Robert Jr. and Kyle Teel. As Civale prepares to join the roster, his track record as a starting pitcher may provide the stability the Sox need as they navigate a challenging season.

The Chicago White Sox faced a tough challenge in Houston against the Astros, coming close but ultimately falling 4-3. Mike Tauchman ignited hope with a ninth-inning home run, reducing the deficit to one run. The Sox battled throughout the game, with Edgar Quero driving in two runs and Miguel Vargas doubling off the wall as they threatened a comeback. However, Astros closer Josh Hader struck out Austin Slater to seal the victory, marking yet another series loss for the Sox against Houston.

Despite the loss, manager Will Venable praised his team's effort, signaling a growing frustration over losing close games. Sox starter Davis Martin expressed the need for better momentum management, particularly after giving up runs immediately following their scoring efforts. The performance showcased both the potential of the Sox’s offense and the challenges they face in closing out games against elite pitchers like Framber Valdez, who managed to keep the Sox at bay despite their eight-hit performance against him.

Hello June! With 11 MLB games slated for Sunday, this is a prime opportunity for DFS players to make their moves. Starting pitchers to watch include Clay Holmes from the New York Mets, who has adapted well to a starting role with a solid 2.98 ERA, facing a struggling Colorado Rockies lineup.

Ranger Suarez of the Philadelphia Phillies is another strong option, boasting a 2.97 ERA against a Milwaukee Brewers team that he can neutralize, especially against left-handed hitters. Adrian Houser from the Chicago White Sox, although a gamble, faces a Baltimore Orioles team struggling to score runs.

From the lineup perspective, Rafael Devers is on fire with a 1.180 OPS and stands to capitalize on a matchup against Braves’ pitcher Bryce Elder, who has shown vulnerability to home runs. Corey Seager continues to produce against righties, providing solid value against Erick Fedde. As for budget options, George Springer brings potential against Oakland's JP Sears, while Miguel Vargas has also been a surprise power source this season.

This week’s fantasy baseball waiver wire pickups focus on infield-eligible players who can provide value as we head into Week 10. Key highlights include Miguel Vargas from the Chicago White Sox, who is on a hot streak with consistent hitting, making him a solid option for teams needing depth at first base or third base. Jonathan India of the Kansas City Royals is also notable, particularly for his favorable matchups against Miles Mikolas, which could bolster his already improving stats. The Minnesota Twins' Carlos Correa is coming off an injury strong, with a high upside for the upcoming week against weaker pitching. Deep league managers should keep an eye on Otto Lopez of the Miami Marlins, who is showing signs of life post-injury, particularly in stolen bases.